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Phase 2 reported -24.2% body weight at 48 weeks at 12 mg, and Phase 3 TRIUMPH-4 reported up to -28.7% at 68 weeks at 12 mg

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When prescribed correctly, glutathione benefits significantly outweigh potential risks for suitable candidates

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In summary, alterations at the glutathione activator site result in an absent geometric and electrostatic complementary 3,50 for the reducing agent, explaining the inefficient reduction of numerous glutaredoxins 12,25,26,27,28,29,48 and thioredoxins by GSH