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Participants on the highest dose (12 mg weekly) lost an average of 24.2% of their body weight over 48 weeks, roughly 58 pounds for someone starting at 240

Moreover, a potential contribution from surveillance bias cannot be excluded

Over a significant period of time, youll eat fewer calories than youll burn on a daily basis

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Yet, despite the preference for DA production, -cells and -cells still express adrenergic receptors, and for some receptor subtypes, to a significantly greater degree relative to D2R/D3R