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Cardiac and renal effects of sodium-glucose co-transporter 2 inhibitors in diabetes: JACC state-of-the-art review

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Why MT-1 Never Went Mainstream (The Real Reason) It actually did get FDA approval but only as Afamelanotide (brand name Scenesse), an implant for a rare disorder called erythropoietic protoporphyria (EPP)

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Regarding cerebrovascular outcomes, statin use significantly decreased the occurrence of major cerebrovascular events (OR 0.82, 95% CI 0.770.87) across all populations, with no statistically significant differences between individual agents

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