Food and Drug Administration (FDA) approved aducanumab as the first disease-modifying therapy (DMT) for AD in June 2021, 10 there has been considerable medical and scientific controversy regarding its curative effect
and prebiotic fiber from certain legumes, whole grains, and fruits
This method ensures maximum systemic availability and allows patients to experience its benefits more efficiently
Under normal conditions, NF-B is sequestered in the cytoplasm by inhibitory proteins known as IBs
In research models, it has demonstrated enhancements in wound healing by up to 50% faster rates and modulation of gene expression related to tissue remodeling
Given that immune cell accumulation plays a vital role in eye diseases pathogenesis, previous researchers have also studied the effect of GLP-1RAs on macrophages and discovered that it could reduce macrophage infiltration in addition to altering macrophage phenotypes in multiple sclerosis and nephropathy (Chiou et al., 2019