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Synthetic mRNAs, which transiently express functional cystinosin, have demonstrated beneficial and sustained impacts on proximal tubular resorptive function, proteinuria, and kidney morphology in zebrafish after treatment [157]

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Activated G-proteins may stimulate the production of secondary messengers such as cyclic adenosine monophosphate (cAMP) and inositol trisphosphate (IP3)

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