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PubMed 22962027 TB-4 Phase 1 human safety first-in-human randomized, double-blind, single- and multiple-dose Phase 1 of recombinant human thymosin 4 in healthy volunteers, no serious adverse events: PubMed 34346165
Patients receiving b12 for pernicious anemia, neurological conditions, or documented deficiency do not report nausea improvement unless their nausea stemmed from the deficiency itself
Side effects are rare and usually mild
\Cartilage Support: Preclinical data suggest potential benefits for cartilage health (Animal Study)