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By influencing both pathways involved in metabolic regulation, tirzepatide offers a broader approach to managing type 2 diabetes and obesity, potentially leading to better health outcomes

This matters because a diverse, balanced microbiome tends to produce less hydrogen sulfide than one dominated by sulfate-reducing bacteria

3,5 This can result in decreased participation in physical activity, contributing to a cycle of deconditioning and symptom exacerbation

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Clinical trials such as the STEP program (semaglutide) and SURMOUNT trials (tirzepatide) have demonstrated improvements in physical functioning and quality of life scores, which patients often interpret as increased energy