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Safety Considerations Common Mild Side Effects Nausea and stomach discomfort Diarrhea Fishy smell in breath or sweat (rare) Who Should Consult a Doctor First Individuals with heart diseases People with kidney problems Those with hormonal disorders Pregnant and nursing women Research Consideration: TMAO Some studies raise concerns about high levels of L-Carnitine from supplements possibly leading to increased TMAO (trimethylamine-N-oxide) production, which has been associated with higher risk of heart diseases
The presence of thiols in biological samples, such as glutathione, cysteine, and homocysteine, can react with the assay reagents
Other liquids, pills, and powders have an upper limit of bioavailability because of the amount that can pass through the gut or degradation by the digestive system
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Table 1 presents the comprehensive characteristics of the included trials
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