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Overnight hypoglycemia is one of the more common mechanisms, especially in patients with type 2 diabetes on insulin or sulfonylureas, or in patients who skip dinner because of nausea

This hormone helps the body manage blood sugar, appetite, and fullness

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Three new Cochrane reviews find evidence that GLP-1 drugs result in clinically meaningful weight loss, but industry-funded studies raise questions

Adv Exp Med Biol 2024;1460:1-25

Semaglutide was developed based on GLP-1(7-37) backbone, its Lys side chain was modified with a long chain fatty acid, enabling it to bind to plasma albumin for slower drug release