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Excessive amounts of APAP metabolism in the liver generate a toxic intermediate, N-acetyl-p-benzoquinone imine (NAPQI), mainly through the activity of cytochrome P450 enzymes CYP2E1 and CYP1A2

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Impact of age and sex on left ventricular function determined by coronary computed tomographic angiography: results from the prospective multicentre CONFIRM study

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