Injecting more frequently than every 3 hours produces diminishing returns because the somatotroph cells have not had time to resynthesize and store growth hormone for the next pulse
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[Crossref] Li W, Xu RJ, Lin ZY, Zhuo GC, Zhang HH (2009) Effects of a cyclooxygenase-1-selective inhibitor in a mouse model of ovarian cancer, administered alone or in combination with ibuprofen, a nonselective cyclooxygenase inhibitor
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[10] Ipamorelin, based on experimental data, might also elevate growth hormone secretion levels to approximately 80 mIU/l, which appears to be 60 times higher than the levels observed following test model exposure to a placebo