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Future interdisciplinary efforts, including in-depth mechanistic studies, large multicenter long-term follow-up trials, and translational research on precise intervention targets, are needed to address these gaps

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The names of the repository/repositories and accession number(s) can be found below: the anonymised data that support the findings of this study are openly available in Zenodo at 10.5281/zenodo.18457092

Among the most promising medical strategies are the combined use of semaglutide and L-carnitine , a pairing that brings together the benefits of prescription-grade metabolic support and a naturally occurring amino acid derivative known for enhancing cellular energy

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Over-the-counter supplements are not recommended, as they lack the regulated purity and strict dosing accuracy required to safely manage a metabolic condition [9] [10]