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[Correlation of male libido with the levels of serum reproductive hormones]

Using semaglutide without medical necessity and supervision may lead to unnecessary risks

The blood pressure-lowering effects likely result primarily from weight loss, which reduces cardiac workload and peripheral vascular resistance , leading to decreased blood pressure through hemodynamic changes

NICE guidance including Technology Appraisal TA875 (semaglutide 2.4 mg for managing overweight and obesity), Clinical Guideline CG189 (Obesity: identification, assessment and management), and Public Health Guidance PH53 (Weight management: lifestyle services for overweight or obese adults) recommends a structured, tiered approach to weight management

There were 12 SAEs (11 SAEs and one SUSAR) in the trial (Table 4)