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Risks, Side Effects, and What Honest Prescribing Looks Like Common and Expected Side Effects Nausea, vomiting, diarrhea, constipation most common, especially during dose titration Gastric emptying delay with gastroparesis-like symptoms clinically significant for patients on structured meal plans Fatigue, particularly early in treatment Hair thinning with higher doses or prolonged caloric restriction Dehydration secondary to gastrointestinal effects Serious but Less Common Risks Acute pancreatitis requires immediate cessation and medical management Gallbladder disease increased incidence with rapid weight loss Thyroid C-cell tumor risk observed in animal studies

MEJL and MJS have done commercially sponsored research for Novo Nordisk, and MEJL has done paid lecturing for Novo Nordisk

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When this receptor is activated, it sends signals that: Increase insulin release when blood sugar rises (NIH) Reduce glucagon, a hormone that raises blood sugar (NIH) Slow down stomach emptying (NIH) Communicate fullness to the brain (NIH) In simple terms, GLP-1 helps your body decide how much energy to use, store, or stop consuming