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when the intracellular Fe2+ overload exceeds the caching capacity of ferritin, and intracellular free iron generates ROS through the fenton reaction, and glutathione (GSH), one of the critically important antioxidants in cells, is catalyzed by peroxidase to oxidized glutathione (GSSG) during lipid peroxidation, and inhibit lipid peroxidation-induced ferroptosis (119)
It encourages fetal growth, central nervous system development, and proper function of the heart, kidneys and immune system
Additionally, by doping the hydrogel sheet with magnetic nanoparticles, endothelial progenitor cells can be promoted to colonize the wound, enhancing the healing effect of hydrogels (Noh et al., 2019)
Concerning the Ikaros zinc finger gene family, we found expression of genes belonging to this gene family in lymphoblastoid and thymus cell lines and for all genes a lower expression was found, with a prevalence of 2:3 gene expression ratio
Additionally, glutathione supports the activity of other antioxidants, such as vitamins C and E, helping to regenerate them after they have been oxidised
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