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Choosing Between Three Growth Hormone Peptides For anyone weighing sermorelin vs ipamorelin vs tesamorelin, the comparison comes down to receptor family, structure, and depth of evidence: sermorelin and tesamorelin are GHRH analogs, ipamorelin is a selective ghrelin mimetic, and tesamorelin carries the most human clinical data of the three

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Ipamorelin 5 differs in that it generates more acute spikes of GH via its secretagogue receptor activation

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