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Older men experienced reduced diastolic blood pressure and improved exercise-induced femoral blood flow (+11%) and vascular conductance (+14%), whereas women showed no such benefits
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The additive insulinotropic effect of GIP combined with GLP-1 results from direct beta-cell stimulation and enhancement of alpha-to-beta cell paracrine communication, with GIP contributing substantially to postprandial insulin secretion [30,31]
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When there is sufficient reduced glutathione in the cells, they sacrifice themselves to free radicals to protect cellular mitochondria
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