Dexamethasone, in particular, has been linked to metabolic disturbances such as hyperglycemia, insulin resistance, hepatic steatosis, and the development of type II diabetes (Madamsetty et al., 2022)
PLoS One 11 , e0161347 (2016)
AP@home: The Artificial Pancreas Is Now at Home
A prospective randomized controlled trial in healthy individuals showed that diet rich in fermented foods was able to enhance the diversity of the microbiota and significantly reduce the levels of proinflammatory cytokines such as serum interleukin (IL-6) (28)
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Consequently, disruption in GSH metabolism is linked to numerous human diseases including cancer, neurodegenerative diseases, alcoholic liver disease, and aging