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Population specificity

Notoginsenoside Ft1 increases intracellular Ca accumulation, reduces 2+ cAMP levels by activating a signaling network mediated through P2Y receptors, and promotes platelet aggregation, thereby exerting a procoagulant effect

however, it should be considered that the majority of these studies have focused on trekkers at high to extreme altitudes, rather than athlete populations at lowmoderate altitudes

Group 1 used a placebo, group 2 used oral L-carnitine (2 g/d) + acetyl-L-carnitine (1 g/d), group 3 used L-carnitine/acetyl-L-carnitine + 1 x 30-mg cinnoxicam suppository every 4 days

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These quantal dose-response relationships are typical sigmoidal dose-response curves