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The effective exclusivity end date is determined by the last-expiring patent (or regulatory exclusivity) that a generic company cannot design around or successfully challenge

While many neurological conditions exhibit distinct pathologies, oxidative stress is a common factor in their etiology

Soft, blended or even liquid meals are often tolerated best when symptoms are at their worst, she says, suggesting options like "overnight oats, eggs, smoothies, Greek yogurt and protein shakes." She adds that "these types of foods can provide protein, vitamins and minerals, fiber and/or hydration," without demanding too much from digestion

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Adipose tissue contributes to endothelial dysfunction (17) due to secretion of adipokines, paracrine hormones which have a crucial role in the regulation of vascular tone