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In addition, activation of GLP-1Rs has anti-inflammatory effects via stimulation of AMPK, cAMP, endothelial nitric oxide synthase (eNOS), and suppression of chemokine expression (Jin and Liu 2020)
Central GLP-1 receptor signalling accelerates plasma clearance of triacylglycerol and glucose by activating brown adipose tissue in mice
Obesity is linked to a laundry list of additional health problems, and those problems become costly for Virginia's $25 billion a year Medicaid program
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The mice in the HFHC group were fed a high-trans-fat diet [58 kcal% fat w/sucrose Surwit Diet (D12331, lot number: 17082101A10, Research Diets, USA)] combined with water containing high carbohydrates (55% fructose + 45% sucrose, concentration 42 g/L) to establish an animal model of NASH
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