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The 2022 Dimet-Wiley paper in Scientific Reports characterised NNMT inhibition combined with reduced-calorie diet in diet-induced-obesity mouse model systems (PMID 35013352)
Study 2: Ng 2000, original characterization Citation: Ng F.M., Sun J., Sharma L., et al
NAD+ NNMT inhibition and direct NAD+ supplementation both target the NAD+/SAM axis, so they are commonly co-studied
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Further studies are necessary to fully characterize its biological mechanisms, safety profile, and broader applications within biomedical research
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