To sum up, GLP-1 receptor agonists protect neurons through several pathways including the classic cAMP/PKA/CREB pathway, the PI3K/Akt pathway, controlling inflammation, and keeping mitochondria working as shown in Figure 1
Neumann J, Gupta RC, Schmitz W, Scholz H, Nairn AC, Watanabe AM (1991) Evidence for isoproterenol-induced phosphorylation of phosphatase inhibitor-1 in the intact heart
The MHRA advises the public to be vigilant about purchasing medicines online and to only obtain treatments through regulated healthcare providers
GLP-1RAs, which achieved great success in 2023 and draws peoples attention back to obesity treatments and GLP-1 therapies worldwide, was chosen as the breakthrough of year 2023 by Science [2]
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