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Overall, linagliptin significantly reduced the OGTT-associated glucose excursion by 18% (95% CI -26.55, -10.34) in the high GLP-1 group compared with 8% (95% CI -16.09 to 0.24) in the low GLP-1 group ( Figure 2C )

Journal of the American Heart Association , Vol

For reconstitution of lyophilised peptide research compounds with Bacteriostatic Water, add the Bacteriostatic Water to the lyophilised powder vial rather than adding powder to water and this ensures complete powder wetting and dissolution without generating undissolved aggregates

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As a result, many patients now remain on GLP-1 therapies far beyond the timelines traditionally studied in clinical trials