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Prolonged UV exposure can induce matrix metalloproteinase-2 (MMP-2) and MMP-9 activation in basement membrane which can lead to collagen types 4 and 6 degradation and accumulation of more elastic fibers in melasma patients (Inomata et al., 2003)

Duration of Therapy: 17 days Additional Notes: This protocol is designed to be administered up to twice per year

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One study by Mohl and colleagues investigated L-DOPA-induced differences in neural activation between tremor dominant (TD) PD patients and posterior instability/gait difficulty (PIGD) PD patients