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Factors that cause glutathione depletion and accelerate aging include: Nutrient-deficient diet Pollutants in the air and water Environmental toxins in food and personal care products Prescription medications and recreational drugs Chronic stress Trauma Infections Exposure to radiation Minimizing your exposure to harmful elements and optimizing healthy lifestyle behaviors can help prevent glutathione depletion

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The driver may be mast-cell-mediated or systemic rather than NF-B-local, and if so, increasing the dose for additional KPV will not address it see the mast-cell note under Phenotype Considerations

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These peptides promote vasodilation and diuresis while reducing cardiac preload and afterload