Quick answer: Semaglutide, tirzepatide, and retatrutide are three peptides that look related on a slide yet differ substantially in the receptors they activate
In addition to life-sustaining nutrient absorption and excretion, our intestines wield many responsibilities--chief amongst them include regulating pancreatic and stomach secretions, metabolism, nervous system function and behavior ( Figure 1 )
Given the elevated risk of cardiovascular morbidity and mortality in individuals with mood disorders, including bipolar disorder, the cardiovascular benefits associated with GLP-1 agonists could offer another valuable protective mechanism, enhancing the overall health and well-being of patients
These are population-average estimates based on clinical trial data
2023;46(Suppl 1):S140-s157
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