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Weight loss itself can change thyroid hormone requirements, and semaglutide's effect on gastric emptying may alter levothyroxine absorption
Within the cohort, 4.5% of participants in the semaglutide group and 0.8% of participants in the placebo group discontinued treatment due to gastrointestinal events
These formulations might come as sublingual (under-the-tongue) tablets, liquids, or troches
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Mean weight decreased to 97.41 9.38 kg in the IGB only group and to 88.00 8.64 kg in the IGB + semaglutide group ( p = 0.002)