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This warning stems from preclinical studies in rodents that demonstrated dose-dependent and treatment-duration-dependent thyroid C-cell tumors at clinically relevant exposures

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PLoS ONE 8:e61965 Solinas M, Panlilio LV, Justinova Z et al (2006) Using drug-discrimination techniques to study the abuse-related effects of psychoactive drugs in rats

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Suggested Use: Adults take 1 capsule 1-2 times a day on an empty stomach or as directed by your qualified healthcare professional