Taken together, these results suggest that CPP-CAND inhibited the FOXO4-p53 interaction in the nucleus, which enabled the extranuclear transport of p53 and selectively induced apoptosis in senescent cells
Gut health restoration happens through stomach lining protection, ulcer healing, and tight junction repair
Physician communication strategies: Framing peptides as mechanism-based interventions (neurotrophic support, antioxidant enhancement, angiogenesis modulation) rather than "alternative medicine" builds credibility
Gene regulation NAD activates sirtuin proteins, which influence metabolism, stress resistance, and cellular longevity
Nutrients supporting existing cellular functions
This mechanism has been characterised in multiple pre-clinical studies, with particular focus on tendon and ligament repair outcomes