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However, when the regulatory mechanism of the immune system malfunctions and mistakenly attacks the bodys own healthy skin cells or tissues, it is implicated in the pathogenesis of a variety of immune-mediated skin diseases (7)

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Quantitative reverse transcription polymerase chain reaction (qRT-PCR) was performed using the StepOne Real-Time PCR System (Thermo Fisher Scientific, Waltham, MA) and THUNDERBIRD SYBR qPCR Mix (Toyobo)

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