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Weight loss was a well known side effect, which is partly what led to newer versions being licensed specifically for weight management
There is no established pharmacological mechanism by which tirzepatide would directly cause fever or true flu-like syndrome
Once thyroid function stabilizes through antithyroid medication or radioactive iodine treatment, tirzepatide can provide meaningful weight loss supporttypically 1020% of body weight over 12 months in clinical trials
The source matters significantly for results
In the U.S., GLP-1 prescriptions more than doubled in just 18 months, topping nine million by early 2024
People with a history of MTC or MEN 2 should avoid Ozempic
