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Other candidate loci for vitiligo in several ethnicities include FASLG, a member of the TNF superfamily, and GZMB, a protease, both of which point to a role of dysregulated apoptosis in vitiligo

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The copper component is precisely what introduces concern in hepatic impairment

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In addition, the inhibition of AMPK action impaired the protective effect of empagliflozin on ferroptosis in the renal cells of DKD mice [249]