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The most common research protocols build slowly from a small starting dose so users can spot side effects early
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For any compound to work transdermally, it must be small enough to penetrate through multiple skin layers and achieve therapeutic concentrations in the bloodstream
GanetzkyRDStendelCMcCormickEMZolkipli-CunninghamZGoldsteinACKlopstockTet al
Therefore, more interventions and experimental studies are needed to address the existing knowledge gaps (74)
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