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Introduction GLP-1 agonists have long been used in Type 2 Diabetes Mellitus (T2DM) and obesity, with decades of clinical data and real world experience demonstrating significant benefits, including reductions in HbA1c levels, body weight, and cardiovascular risk markers

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Professor Jastreboffs research contributions include: Principal investigator for GLP3 phase 2 obesity trial demonstrating 24.2% weight loss Leadership in clinical research examining triple hormone receptor agonists Extensive investigations of incretin-based therapies for obesity and metabolic disease Pioneering work on combination approaches to weight management Studies examining neurobiological mechanisms underlying obesity pharmacotherapy Her work has helped establish GLP3 as one of the most promising next-generation obesity treatments in clinical development, contributing to the scientific foundation for multi-pathway metabolic interventions

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