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doi: 10.1002/ejp.1397
Without sufficient GSH, ROS can peroxidize lipids and form disulfide bonds in periplasmic proteins, potentially stiffening the membrane or altering porin channels
Nat Aging 5(3):376385
In obese and insulin-resistant rodents, NAD+ levels are reduced in liver and adipose tissue
The most common side effects are gastrointestinal, including nausea (occurring in 20-30% of patients), diarrhea, vomiting, constipation, and abdominal discomfort
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