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Retatrutide may produce greater average weight loss than Mounjaro based on clinical trial data so far, but it is too early to say it is better overall
May Decrease Life Span In certain animal studies conducted on mice, worms and flies, decreased IGF-1 levels actually led to longer life span
Without treatment, pellagra can be fatal, which is an important factor to be considered, since its low prevalence in developed countries causes missed diagnosis and delayed treatments (12, 54)
How can these takeaways inform the efficacy of novel drug development efforts in 2023
Inflammopharmacol 33 , 62656272 (2025)
The peptide does not act on the HPG axis, does not stimulate LH or FSH release, and does not bind to androgen receptors
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