doi: 10.1038/s41588-019-0350-x 35 ReitmeierSKiesslingSClavelTListMAlmeidaELGhoshTSet al
Depression is not a common side effect in clinical trials, but individual reports exist
No modifications or deviations from the original protocol were documented
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GLP-1 drugs are expensive, with list prices exceeding $1,000/month in many markets, and studies consistently show that people who stop taking semaglutide regain roughly two-thirds of the weight they lost, raising fundamental questions about whether these drugs represent treatment or lifelong pharmaceutical dependency
Tirzepatide: activating two receptors Tirzepatide (Mounjaro, Zepbound) takes a different approach