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Ao trmino do estudo, observou-se as seguintes mudanas mdias percentuais no peso corporal: Reduo de 15,0% nas doses de 5 mg de Zepbound, Reduo de 19,5% nas doses de 10 mg de Zepbound, Reduo de 20,9% nas doses de 15 mg de Zepbound, Enquanto o grupo que recebeu placebo apresentou uma diminuio de apenas 3,1% no peso corporal

Increased fat accumulation can lead to inflammation (non-alcoholic steatohepatitis [NASH]) and liver fibrosis, and can further advance to NASH-related cirrhosis, which is the fastest-growing indication for liver transplantation in western countries [10]

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The study of drug metabolism is essential for the safety and efficacy of drug molecules