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The future of surgery lies not just in perfecting operative techniques, but in optimizing the biological processes that determine surgical success

For myocardial hypertrophy, potential decisions include who needs closer follow-up, who is likely to progress to HFpEF, who may regress after pressure unloading, who has metabolically reversible remodeling, who should receive a metabolic intervention, and who is at risk of treatment toxicity

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Abstract Many local and systemic diseases especially diseases that are leading causes of death globally like chronic obstructive pulmonary disease, atherosclerosis with ischemic heart disease and stroke, cancer and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing coronavirus disease 19 (COVID-19), involve both, (1) oxidative stress with excessive production of reactive oxygen species (ROS) that lower glutathione (GSH) levels, and (2) inflammation

When the experiment was quantified in terms of CD31-positive vessels, similar results were obtained

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