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Common returning side effects include nausea (often the most prominent), changes in bowel habits (constipation or diarrhea), reduced appetite that might feel more dramatic than you remember, fatigue during the first few weeks, and occasional headaches

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Less frequently reported adverse reactions (less than 1% or less than twice rate of placebo) included palpitations, diarrhea, nausea, decreased appetite, dizziness, agitation, depression, paranoia and restlessness

What Makes Tirzepatide Different That second pathway is the main mechanical difference

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