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NRF2 is a member of the cap n collar (CNC)-bZip transcription factor family that upon recognition of the antioxidant response cis element (ARE) heterodimerizes with small musculoaponeurotic fibrosarcoma (sMAF) proteins to activate transcription (Igarashi et al, 1994
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This enhanced vascularization delivers more oxygen, nutrients, and healing factors to damaged tissues
As a potent anti-oxidant, Glutathione also kills the harmful free radicals in the body
Metal-Mediated Signaling: Delivers bioavailable Cu to copper-dependent enzymes and pathways (e.g., lysyl oxidase family) that participate in cross-linking and tissue architecture
PMID: 40573323
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