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In rodent models, behavioral hyperactivity, stereotypy (repetitive non-functional movements), hyperthermia, and muscle rigidity are the primary indicators
Limitations The present study has several limitations
Due to neurons having a limited capacity for GSH synthesis, they must rely on astrocytes to supply precursors such as cysteine (Prez-Sala D and Pajares, 2023)
It signals fibroblasts (the cells responsible for tissue repair) to increase synthesis of: collagen, the main protein responsible for the strength and elasticity of skin and connective tissue
Mass Spectrometry Reviews 32 , 399415 (2013)
Challenges with peptide-based therapies for back pain To probe whether this peptide might be used as a drug therapy to delay or prevent degeneration, the team treated mice with the peptide for four consecutive weeks
