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Those hardened lumps are not just unsightly

Approaches like perfusion machine pre-treatments adding agents like trimetazidine (a metabolic modulator) aim to improve mitochondrial fatty acid oxidation during preservation, thus reducing IR damage when implanted

It targets both GLP-1 and GIP (gastric inhibitory polypeptide) receptors to trigger enhanced metabolic effects

Despite insurance coverage for many patients, approximately 54% of users report difficulty affording the medications ^19

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