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A 2024 study of more than 16,000 patients found that using semaglutide drugs like Wegovy or Ozempic was associated with increased diagnoses of NAION
A 2008 study published in the Journal of Medicinal Chemistry demonstrated metabolic effects in rodent models at 50mg/kg, which led early researchers to extrapolate human-equivalent doses between 50100mg daily
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Once-Weekly Semaglutide in Adults with Overweight or Obesity New England Journal of Medicine 384(11) 2021PMID: 33567185 NEJM 4 Jastreboff AM, Aronne LJ, Ahmad NN, et al
Powell, L
Neutrophils, mononuclear phagocytes, and lymphocytes accumulate vitamin C to high concentrations, which can protect these cell types from oxidative damage (12-14)
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