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Once inside cells, glutathione binds to free radicals, heavy metals, and toxins, converting them into harmless compounds that are eliminated by the liver and kidneys

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Almost all efficacy data come from a single research group, and independent replication of the larger-effect-size studies remains limited

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For example, in the SELECT trial (17,600 patients with cardiovascular disease and obesity but without T2D), weekly subcutaneous Semaglutide (2.4 mg) reduced the risk of major adverse cardiovascular events (MACE heart attack, stroke, or cardiovascular death) by 20% compared to placebo (HR 0.80

3,4 Referred to as the incretin effect , they exert their effects by binding to their respective receptors of the pancreas beta cells to ultimately release insulin