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96 Common dental diseases include periodontal disease/gingivitis, tooth fracture or loss, oral masses, and retained deciduous (baby) teeth

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However, in high gastrointestinal risk scenarios, clinicians may consider holding the weekly dose for 7 days before the procedure

The lower RMSF values for residues 200 to 400 in the Arbutin_d mode are hypothesized to be due to the hydroxyphenyl group of Arbutin_d facing the L3 region, where R289 tends to interact with the hydroxyphenyl group of Arbutin, stabilizing this region

After coadministration at week 4, there was no meaningful impact on acetaminophen Cmax and tmax

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