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BPC-157 acts primarily on the nitric oxide (NO) system , VEGF-mediated angiogenesis and gastric mucosal protection pathways central to vascular repair, tendon-to-bone healing, and gastrointestinal models

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Materials and methods Animals Wistar albino male rats (aged 12 weeks, 350400 g b.w.) were bred in-house (the animal facility at the Department of Pharmacology, School of Medicine, Zagreb, Croatia

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Important safety considerations include risks of acute pancreatitis (seek medical attention for severe abdominal pain with or without vomiting), gallbladder disease, dehydration, and potential worsening of diabetic retinopathy with rapid improvement in glucose control