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Antibodies to intrinsic factor and parietal cells are just two of the causes of malabsorption

At least, nine members of TRP superfamily are activated by oxidative stress including TRPM2, TRPM7, TRPA1, TRPC3, TRPC5, TRPC6, TRPV1, TRPV3, and TRPV4 (Ogawa et al., 2016)

doi: 10.1098/rsob.200200 190 KimD-GJungKHLeeD-GYoonJ-HChoiKSKwonSWet al

Diabetes was induced by streptozotocin (STZ) (60 mg/kg, Intraperitoneal), and neuropathy was confirmed by hyperalgesia testing

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Flexibility in the Insulin Receptor Ectodomain Enables Docking of Insulin in Crystallographic Conformation Observed in a Hormone-Bound Microreceptor