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In these procedures, which usually last for less than an hour and are normally performed on an outpatient basis, surgeons make a small incision on the lens, disrupt the lens either ultrasonically or by using lasers, and insert the IOL into the capsule bag where the natural lens used to be located (Medline 2012)

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The accumulation factor at steady state is approximately 1.7-fold, meaning your trough level at steady state is about 1.7 times what it would be from a single dose

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The human skin is not only an estrogen target but also a primary estrogen source